PHARMACY RECORDS WHITE PAPER 2025
TOP 10 U.S. PHARMACIES BY REVENUE
The U.S. pharmacy market is dominated by a few major players that account for the majority of prescription dispensing revenue. Below is a list of the top 10 pharmacies based on prescription
dispensing revenues and their estimated market shares.
Top 10 U.S. Pharmacies by Revenue
| Rank | Pharmacy | Market Share (%) |
|---|---|---|
|
1 |
CVS Health Corp. |
24% |
|
2 |
Walgreens Boots Alliance |
14% |
|
3 |
Cigna (Evernorth/Express Scripts) |
10% |
|
4 |
UnitedHealth Group
(OptumRx) |
6% |
|
5 |
Walmart Stores |
5% |
|
6 |
Kroger |
2% |
|
7 |
Rite Aid Corp. |
2% |
|
8 |
Humana (CenterWell) |
2% |
|
9 |
Albertsons |
1% |
|
10 |
Publix |
1% |
These top 10 pharmacies account for approximately 67% of the U.S. prescription dispensing market. CVS Health, Walgreens Boots Alliance, and Cigna alone represent nearly half of the market. Mergers, acquisitions, and financial shifts continue to shape the competitive landscape, with major companies such as Kroger and Albertsons exploring potential mergers.
Amazon Pharmacy
Amazon Pharmacy aims to offer same-day delivery to half of the country by the end of 2025. One of the reasons Amazon created their mail-order pharmacy is due to pharmacy deserts, which are locations which don’t have a physical pharmacy within 10 miles. Patients in these areas are more likely to choose mail order pharmacies like Amazon.
Access to Amazon Prescriptions
Amazon Pharmacy
The following categories of medications are not available through Amazon Pharmacy:
- Schedule II-controlled medication: hydromorphone (Dilaudid®), methadone
(Dolophine®), meperidine (Demerol®), oxycodone (OxyContin®, Percocet®), fentanyl
(Sublimaze®, Duragesic®), morphine, opium, codeine, and hydrocodone. - Compounded medications
- Medical devices (braces, insulin pumps, nebulizers)
- Pet prescriptions
- REMS medications
- Suspensions (liquid amoxicillin, fluconazole)
- Vaccines
Authorization to disclose information:
According to the Amazon Privacy Notice, Workers’ Compensation is one of the reasons
they disclose information. – “We may disclose Protected Health Information about you for
workers’ compensation or similar programs that provide benefits for work-related
injuries or illness.”
